One of the most common mold toxins (mycotoxins) known to Man, aflatoxin B - found in peanuts - has been shown to be a powerful carcinogen.
Drs. Wang and Groopman from the Environmental Health Sciences Department at Johns Hopkins, authored an article in 1999 on the effects of mold toxins on DNA. It was published in Mutation Research -- a leading cancer journal.
From the article:
"Mycotoxins are toxic fungal metabolites which are structurally diverse, common contaminants of the ingredients of animal feed and human food.
"To date, mycotoxins with carcinogenic potency in experimental animal models include aflatoxins, sterigmatocystin, ochratoxin, fumonisins, zearalenone, and some Penicillium toxins...
"Aflatoxin B1 [is] a Category I known human carcinogen and the most potent genotoxic agent, is mutagenic in many model systems and produces chromosomal aberrations, micronuclei, sister chromatid exchange, unscheduled DNA synthesis, and chromosomal strand breaks, as well as forms adducts in rodent and human cells....More strikingly, the relationship between aflatoxin exposure and development of human hepatocellular carcinoma ... was demonstrated by [other] studies..."
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Drs. Wang and Groopman from the Environmental Health Sciences Department at Johns Hopkins, authored an article in 1999 on the effects of mold toxins on DNA. It was published in Mutation Research -- a leading cancer journal.
From the article:
"Mycotoxins are toxic fungal metabolites which are structurally diverse, common contaminants of the ingredients of animal feed and human food.
"To date, mycotoxins with carcinogenic potency in experimental animal models include aflatoxins, sterigmatocystin, ochratoxin, fumonisins, zearalenone, and some Penicillium toxins...
"Aflatoxin B1 [is] a Category I known human carcinogen and the most potent genotoxic agent, is mutagenic in many model systems and produces chromosomal aberrations, micronuclei, sister chromatid exchange, unscheduled DNA synthesis, and chromosomal strand breaks, as well as forms adducts in rodent and human cells....More strikingly, the relationship between aflatoxin exposure and development of human hepatocellular carcinoma ... was demonstrated by [other] studies..."
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