SAN FRANCISCO — Mold infested civic and private buildings after rainwater leaked for years through a flawed joint in the Metreon.

The building in the South of Market neighborhood was designed as a kingdom for gamers, but it now languishes with a large vacancy rate and an identity crisis.

Plans to turn the hulking building into an eating destination failed recently, and the latest rejuvenation efforts rely on attracting large retail tenants such as Target.

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